In 1748, William Cullen of Glasgow University, UK established for the first time, the artificial refrigeration.

In 1851, John Gorrie invented the first ice-making machine. Ice baths rapidly became a popular method of cooling reactions and other lab processes, and this low-tech technique is still frequently used today.

In 1876, German engineer Carl von Linde invented a continuous process of liquefying large volumes of gas. This invention ultimately made chilling and refrigeration possible on a domestic and industrial scale and laid the base for the development of the modern refrigeration industry.

In 1921, an inventor named Willis Carrier patented the first centrifugal water chiller. Before this time, chillers used a reciprocating compressor to move the refrigerant through the system. The main part of a centrifugal chiller is the centrifugal compressor. The design of the first centrifugal compressor was similar to the centrifugal blades in a water pump.

In 1950, the plastics industry designed the first industrial chiller.